Nasal Delivery of Therapeutics and Vaccines

The anatomy and physiology of the nasal cavity creates a number of unique opportunities for the successful delivery of drugs and vaccines. This can be locally, systemically or directly to the central nervous system. This utility has resulted in growing interest from scientists looking to administer both therapeutic agents and vaccines via the nasal delivery … Read more

Key Considerations when Choosing a Device for Dry Powder Nasal Delivery

Drug administration via the nasal route can be used as an efficient method of administration for both local and systemic acting drugs. The nasal route offers a range of advantages including its relative ease of use as compared to injectable administration, patient acceptability and compliance. It also provides a suitable route for those compounds that … Read more

Stages of Tablet Development: Compression Equipment Overview

Stages of Tablet Compression Equipment Used During Formulation and Process Development Tablets are one of the most popular dosage forms used in the pharmaceutical, nutraceutical and veterinary industries due to their ease of handling and administration, stability, convenient packing options and well-established cost-effective manufacturing processes which produce consistent quality products. Developing a tablet formulation from … Read more

Upperton is Launching an Enabling Technology Screening Protocol – UpperSolv

10th December 2019 – Press Release Upperton Pharma Solutions, a UK-based contract development and manufacturing organisation (CDMO) are launching an enabling technology screening protocol which aims to support companies with the rapid development of both standard and complex drug products. The new enabling technology screening protocol, integrates the company’s existing formulation capabilities with a biopharmaceutical … Read more

Using Spray Drying to Develop Inhaled Dosage Forms

Pulmonary delivery is showing increased popularity as a viable dosage form for treating local airway diseases and offers additional potential for systemic drug delivery. Within this space there are a number of delivery approaches that can be undertaken. These include dry powder inhaled formulations (DPI) and pressurised metered Dose Inhalers (pMDIs). Each of these delivery … Read more

Upperton Pharma Solutions Investment Increases Tabletting Capabilities

17th September 2019 – Press Release In recent weeks Upperton has been focussing heavily on enhancing our formulation capabilities (through increased tabletting capabilities) with a series of investments in new equipment for our R&D and QC laboratories. This is now being followed by our largest ever capital investment programme aimed at bringing in new manufacturing … Read more

MHRA Inspection success for Nottingham’s Upperton Pharma Solutions

8th January 2019 – Press Release Upperton Pharma Solutions’ new pharmaceutical spray drying manufacturing facilities at Nottingham Science and Technology Park have successfully passed inspection by the UK Medicines and Healthcare products Regulatory Agency (MHRA). A pharmaceutical spray drying contract development and manufacturing organisation (CDMO), Upperton Pharma Solutions moved to its new facilities on Nottingham … Read more

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